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Symbol Name ID |
Nfatc1
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 MGI:102469 |
| Darker colors indicate more annotations |
| Mouse Phenotypes | increased B cell apoptosis |
abnormal osteoclast differentiation |
decreased B cell proliferation |
abnormal class switch recombination |
increased double-negative T cell number |
decreased double-positive T cell number |
anemia |
abnormal lymphocyte cell number |
decreased B-1a cell number |
decreased B cell number |
decreased lymphocyte cell number |
decreased osteoclast cell number |
abnormal lymphocyte physiology |
abnormal B cell physiology |
abnormal immunoglobulin level |
increased IgA level |
decreased IgE level |
decreased IgG1 level |
decreased IgG2a level |
increased IgG2a level |
decreased IgG2b level |
decreased IgG3 level |
decreased IgM level |
increased IgM level |
decreased immunoglobulin level |
increased immunoglobulin level |
abnormal marginal zone B cell physiology |
abnormal T cell physiology |
abnormal T-helper 2 physiology |
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| Availability | Mouse Genotype | |||||||||||||||||||||||||||||
| Nfatc1tm1Mak/Nfatc1tm1Mak | ||||||||||||||||||||||||||||||
| Nfatc1tm1Glm/Nfatc1tm2Glm | ||||||||||||||||||||||||||||||
| Nfatc1tm1Rao/Nfatc1tm1Rao Cd79atm1(cre)Reth/Cd79a+ (conditional) |
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| Nfatc1tm1Rao/Nfatc1tm1Rao Tg(Fcer2a-cre)5Mbu/0 (conditional) |
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| Nfatc1tm3Glm/Nfatc1tm3Glm Tg(Mx1-cre)1Cgn/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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